do glp 1 affect bone density New Research on GLP-1s & Health 🦴 ​A new large-scale study has raised questions about the long-term effects of GLP-1 receptor agonists (like Ozempic and Wegovy). While these medications are revolutionary Study reveals exercise and GLP-1

doi: 10.1084/jem.20151159 36 BerodLFriedrichCNandanAFreitagJHagemannSHarmrolfsKet al

One area of theoretical concern relates to altered drug absorption

Gorobets O, Gorobets S, Polyakova T, et al

Conclusion Both semaglutide tablets and injections have proven effective for weight loss and managing type 2 diabetes

Consider two people who both lose 15 kilograms on a GLP-1 drug: Lost 15 kg but poorly 10 kg fat lost 5 kg muscle lost Metabolic rate has fallen Blood sugar control worsened Higher fall risk than before Weight regain likely as fat Lost 15 kg and well 14 kg fat lost 1 kg muscle lost (or neutral) Metabolic rate preserved Blood sugar control improved Strength maintained or increased Better long-term weight maintenance Both people lost the same amount of weight by the scale